- The More I See – Complete the Tutorials
- James Hetfield – Complete the career as the vocalist
- Lars Ulrich – Complete the career as the drummer
- Kirk Hammett – Complete the career as the guitarist
- Robert Trujillo – Complete the career as the bassist
- One – Complete a song with any instrument on Hard or Expert in local Quickplay or Career
- SECRET Damage Inc. – Perform as the drummer
- SECRET Motorbreath – Perform as the vocalist
- SECRET Invisible Kid – Perform as the bassist
- SECRET Some Kind of Monster – Perform as the guitarist
- Ride the Lightning – All band members trigger star power simultaneously (4 player band)
- 2 X 4 – Earn a band Hot Streak (4 player band)
- SECRET Master of Puppets – Earn the highest individual score on a song in a band (4 player band)
- The Struggle Within – Complete a song in a band in Quickplay or Career (4 players)
- The Four Horsemen – Complete a song with all band members on expert in Quickplay or Career (4 player band)
- SECRET Black – Win an online battle match with the Fade to Black power up
- Better Than You – Win an online Pro Face-Off match
- Blitzkrieg – Win an online Band v Band match (8 players)
- Seek & Destroy – Play 20 online matches
- The Unforgiven – Win an online Face-Off match
- SECRET The Unforgiven II – Win an online Face-Off match by 25,000 points or more
- SECRET The Unforgiven III – Win an online Pro Face-Off match by 25,000 points or more
- Reload – Download a song from GHTunes
- SECRET Cure – Recover from a poor performance in Quickplay or Career
- SECRET Disposable Heroes – Create a new custom rocker
- SECRET Blackened – Create a new custom tattoo
- SECRET Eye of the Beholder – Create a new custom band logo
- SECRET Fixxxer – Create a new custom instrument (guitar, drums, mic)
- Hero of the Day – Complete a song on Expert + in Quickplay or Career (drums only)
- SECRET The House Jack Built – Complete a song in every In-the-Round venue
- Wherever I May Roam – Complete a song in every venue
- SECRET Trapped Under Ice – Complete a song at the Ice Cave venue
- SECRET Stone Dead Forever – Complete a song at The Stone venue
- SECRET King Diamond – Rock out as King Diamond
- SECRET Lemmy – Rock out as Lemmy
- The Memory Remains – View a Metallifacts video
- SECRET Astronomy – Hit every star phrase in the song Orion
- Metallica – Complete any instrument career on Expert (Guitar, Bass, Vocals, Drums or Band)
- …And Justice for All – Earn 100 stars in Band Career or any single instrument Career
- The Ecstacy of Gold – Earn $15,000
- Metal Militia – 100% a song (4 player band)
- Nothing Else Matters – Complete the career in a band (2-4 player band)
- SECRET Green Hell – Drum every green note and finish the song Blood and Thunder with the rock meter in green
- SECRET Creeping Death – Score 575,000 on the song Creeping Death as the guitarist
- SECRET Dyer’s Eve – Score 450,000 on the song Dyer’s Eve as the drummer
- SECRET Fight Fire with Fire – Score 340,000 on the song Fight Fire with Fire as the bassist
- SECRET Stone Cold Crazy – Score 65,000 on the song Stone Cold Crazy as the vocalist
- SECRET Enter Sandman – Score 330,000 on the song Enter Sandman on guitar
- SECRET Battery – Score 1,000,000 on the song Battery as a band (4 players)
- Holier Than Thou – Complete all instrument careers
- Platinum Artist – Earn all of the Bronze, Silver and Gold Trophies in Guitar Hero Metallica
Releasedatum: 22-05-2009
Genre: Educatief
Uitgever: Activision
Ontwikkelaar: Neversoft
Meer Guitar Hero: Metallica