- Is There a Way Out? – Complete Chapter 1.
- San Francisco is safe, next! – Complete Chapter 2.
- Could we Fight Something Bigger? – Complete Chapter 3.
- What Alien Menace? – Complete Chapter 4.
- Flying Fish – Perform 50 Leap Attacks with The Missing Link.
- Stay Put and Watch – Watch credits until the end.
- Casual Collector – Collect 100,000 Monsters DNA particles in the game.
- Full Arsenal – Buy all upgrades for all characters (Green nodes).
- Two is Better than One – Buy all coop upgrades.
- Art Aficionado – Buy every concept art.
- Shopping Frenzy – Buy all surprises (Purple nodes).
- That’s a Blast – Use the Charge Blast for the first time in Coop.
- Strong Attraction – Use the Tractor Beam for the first time in Coop.
- Collateral Damage – Destroy 30 EyeScouts and Helicopters in Ginormica’s levels in Coop.
- Air Support Master – Destroy 100 BHolders in The Missing Link’s and B.O.B.’s levels in Coop.
- Maximum Attraction – Tractor Beam 50 enemies in The The Missing Link’s and B.O.B. levels in Coop.
- Great Tackler – Destroy 10 drones with Ginormica’s dash.
- Master Tackler – Destroy 25 drones with Ginormica’s dash.
- Get Out of the Way – Use Ginormica’s Chain Dash for the first time.
- Bring it On – Defeat a Beam Bot without getting hurt.
- Just Warming Up – Defeat 50 enemies with The Missing Link.
- Can’t Get Enough! – Defeat 100 enemies with The Missing Link.
- Bull Rider – Destroy 10 Turrets using the Rodeo mode while climbing with The Missing Link.
- Cowboy Master – Destroy 30 Turrets using the Rodeo mode while climbing with The Missing Link.
- Strike with Attitude – Use The Missing Link’s Leap Attack for the first time.
- Expert Pitcher – Throw 25 enemies with The Missing Link.
- Pinball Fan – Use the Bumpers for the first time.
- Around the World – Use the Pole Vault for the first time.
- Glutton – Swallow 20 enemies/objects with B.O.B.
- Machine gun specialistComplete one B.O.B. Turret sequence without being hurt.
- Safety First – Activate B.O.B.’s Shield for the first time.
- Olympic Champion – Get any Medal for all Monster Challenges.
- My Thumb Hurts – Get a score of 5,000,000.
- SECRET Team Spirit – Complete Chapter 1 without failing more than 10 times.
- SECRET Team Victory – Complete Chapter 2 without failing more than 10 times.
- SECRET Defying Gravity – Jump 150 times with each monster.
- Not a Novice Anymore – Complete the game (awarded just before credits).
- Could I be any better than this? – Defeat 300 enemies with The Missing Link.
- Gourmet – Swallow 50 enemies/objects with B.O.B.
- SECRET Team Glory – Complete Chapter 3 without failing more than 10 times.
- SECRET Team Supremacy -Complete Chapter 4 without failing more than 10 times.
- Gold Olympic Champion – Get a Gold Medal for all Monster Challenges.
- Be My Guest – Get a score of 10,000,000.
- Never Say Enough – Collect 500,000 Monsters DNA particles in the game.
- SECRET Remember the Heroes – Complete the game without failing more than 10 times.
- SECRET Monsters vs Aliens Champion – Unlock all 45 trophies to earn this.